Impact of brain-derived neurotrophic factor Val66Met polymorphism on cortical thickness and voxel-based morphometry in healthy Chinese young adults.

doi:10.1371/journal.pone.0037777

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Impact of brain-derived neurotrophic factor Val66Met polymorphism on cortical thickness and voxel-based morphometry in healthy Chinese young adults.

PloS one - 1 Jan 2012

Yang Xuejuan, Liu Peng, Sun Jinbo, Wang Guihong, Zeng Fang, Yuan Kai, Liu Jixin, Dong Minghao, von Deneen Karen M, Qin Wei, Tian Jie

Abstract excerpt

BACKGROUND: Following voxel-based morphometry (VBM), brain-derived neurotrophic factor (BDNF) Val66Met polymorphism (rs6265) has been shown to affect human brain morphology in Caucasians. However, little is known about the specific role of the Met/Met genotype on brain structure. Moreover, the relationship between BDNF Val66Met polymorphism and Chinese brain morphology has not been studied. METHODOLOGY/PRINCIPAL...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain-Derived Neurotrophic Factor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cerebral Cortex

Share to China

Share to Magnetic Resonance Imaging

Share to Methionine

Share to Polymorphism, Genetic

Share to Valine

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 22719849
DOI: 10.1371/journal.pone.0037777
PMCID: PMC3374831

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impact of brain-derived neurotrophic factor Val66Met polymorphism on cortical thickness and voxel-based morphometry in healthy Chinese young adults.PMID 22719849Read ↗

Effect of the BDNF Val66Met polymorphism on regional gray matter volumes and cognitive function in the Chinese population.Semantic proximity Read ↗

Effects of the BDNF Val66Met Polymorphism on Gray Matter Volume in Typically Developing Children and Adolescents.Semantic proximity Read ↗

Association between the brain-derived neurotrophic factor Val66Met polymorphism and brain morphology in a Japanese sample of schizophrenia and healthy comparisons.Semantic proximity Read ↗

Effects of the brain-derived neurotropic factor variant Val66Met on cortical structure in late childhood and early adolescence.Semantic proximity Read ↗

Brain-derived neurotrophic factor polymorphisms and frontal cortex morphology in schizophrenia.Semantic proximity Read ↗

Relationship between a BDNF gene polymorphism and the brain volume in treatment-naive patients with major depressive disorder: A VBM analysis of brain MRI.Semantic proximity Read ↗

Dosage effects of BDNF Val66Met polymorphism on cortical surface area and functional connectivity.Semantic proximity Read ↗

Brain-derived neurotrophic factor Val66Met polymorphism affects cortical thickness of rostral anterior cingulate in patients with major depressive disorder.Semantic proximity Read ↗

The BDNF Val66Met polymorphism is associated with structural neuroanatomical differences in young children.Semantic proximity Read ↗

Structural neuroimaging correlates of allelic variation of the BDNF val66met polymorphism.Semantic proximity Read ↗

A Meta-Analysis of Brain-Derived Neurotrophic Factor Effects on Brain Volume in Schizophrenia: Genotype and Serum Levels.Semantic proximity Read ↗

The association of the BDNF Val66Met polymorphism and the hippocampal volumes in healthy humans: a joint meta-analysis of published and new data.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.