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Article

Altered white matter architecture in BDNF met carriers.

PloS one - 1 Jan 2013

Ziegler Erik, Foret Ariane, Mascetti Laura, Muto Vincenzo, Le Bourdiec-Shaffii Anahita, Stender Johan, Balteau Evelyne, Dideberg Vinciane, Bours Vincent, Maquet Pierre, Phillips Christophe

Abstract excerpt

Brain-derived neurotrophic factor (BDNF) modulates the pruning of synaptically silent axonal arbors. The Met allele of the BDNF gene is associated with a reduction in the neurotrophin's activity-dependent release. We used diffusion-weighted imaging to construct structural brain networks for 36 healthy subjects with known BDNF genotypes. Through permutation testing we discovered clear differences in connection...

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Identifiers

PMID: 23935975
DOI: 10.1371/journal.pone.0069290
PMCID: PMC3729843

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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