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Article

Regulatory genomic regions active in immune cell types explain a large proportion of the genetic risk of multiple sclerosis.

Journal of human genetics - 1 Apr 2014

Elangovan Ramyiadarsini I, Disanto Giulio, Berlanga-Taylor Antonio J, Ramagopalan Sreeram V, Handunnetthi Lahiru

Abstract excerpt

There is little understanding of how genetic variants discovered in recent genome-wide association studies are involved in the pathogenesis of multiple sclerosis (MS). We aimed to investigate which chromatin states and cell types explain genetic risk in MS. We used genotype data from 1854 MS patients and 5164 controls produced by the International Multiple Sclerosis Genetics Consortium and Wellcome Trust Case...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Enhancer Elements, Genetic

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Identifiers

PMID: 24522295
DOI: 10.1038/jhg.2014.3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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