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Article

Impact of genetic risk loci for multiple sclerosis on expression of proximal genes in patients.

Human molecular genetics - 1 Mar 2018

James Tojo, Lindén Magdalena, Morikawa Hiromasa, Fernandes Sunjay Jude, Ruhrmann Sabrina, Huss Mikael, Brandi Maya, Piehl Fredrik, Jagodic Maja, Tegnér Jesper, Khademi Mohsen, Olsson Tomas, Gomez-Cabrero David, Kockum Ingrid

Abstract excerpt

Despite advancements in genetic studies, it is difficult to understand and characterize the functional relevance of disease-associated genetic variants, especially in the context of a complex multifactorial disease such as multiple sclerosis (MS). As a large proportion of expression quantitative trait loci (eQTLs) are context-specific, we performed RNA-Seq in peripheral blood mononuclear cells from MS patients...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29325110
DOI: 10.1093/hmg/ddy001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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