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Vitamin D receptor binding, chromatin states and association with multiple sclerosis

16 May 2012

Abstract excerpt

Both genetic and environmental factors contribute to the aetiology of multiple sclerosis (MS). More than 50 genomic regions have been associated with MS susceptibility and vitamin D status also influences the risk of this complex disease. However, how these factors interact in disease causation is unclear. We aimed to investigate the relationship between vitamin D receptor (VDR) binding in lymphoblastoid cell...

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PMID: 22595971
DOI: 10.1093/hmg/dds189

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