Article
Edc3 function in yeast and mammals is modulated by interaction with NAD-related compounds.
G3 (Bethesda, Md.) - 16 Apr 2014
Walters Robert W, Shumilin Igor A, Yoon Je-Hyun, Minor Wladek, Parker Roy
Abstract excerpt
The control of mRNA translation and degradation is mediated in part by a set of proteins that can inhibit translation and promote decapping, as well as function in the assembly of cytoplasmic mRNP granules referred to as processing bodies (P-bodies). The conserved enhancer of mRNA decapping 3 (Edc3) protein functions to promote both decapping and P-body assembly. Crystal structures of the YjeF_N domain in hEdc3...
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