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Article

Targeted mRNA degradation by deadenylation-independent decapping.

Molecular cell - 2 Jul 2004

Badis Gwenael, Saveanu Cosmin, Fromont-Racine Micheline, Jacquier Alain

Abstract excerpt

Modulating the rate of mRNA degradation is a fast and efficient way to control gene expression. In a yeast strain deleted of EDC3, a component of the decapping machinery conserved in eukaryotes, the transcript coding the ribosomal protein Rps28b is specifically stabilized, as demonstrated by micr...

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Identifiers

PMID: 15225544
DOI: 10.1016/j.molcel.2004.06.028

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15225544-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

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Targeted mRNA degradation by deadenylation-independent decapping.PMID 15225544Read ↗

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Premature translational termination triggers mRNA decapping.Semantic proximity Read ↗

New insights into the control of mRNA decapping.Semantic proximity Read ↗

DDX3 depletion represses translation of mRNAs with complex 5' UTRs.Semantic proximity Read ↗

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Analysis of mutations in the yeast mRNA decapping enzyme.Semantic proximity Read ↗

Yeast Sm-like proteins function in mRNA decapping and decay.Semantic proximity Read ↗

Stm1 modulates mRNA decay and Dhh1 function in Saccharomyces cerevisiae.Semantic proximity Read ↗

Rapid deadenylation triggered by a nonsense codon precedes decay of the RNA body in a mammalian cytoplasmic nonsense-mediated decay pathway.Semantic proximity Read ↗

mRNA decapping in yeast requires dissociation of the cap binding protein, eukaryotic translation initiation factor 4E.Semantic proximity Read ↗

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