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Article

A role of VAMP8/endobrevin in regulated exocytosis of pancreatic acinar cells.

Developmental cell - 1 Sept 2004

Wang Cheng-Chun, Ng Chee Peng, Lu Lei, Atlashkin Vadim, Zhang Wei, Seet Li-Fong, Hong Wanjin

Abstract excerpt

Despite our general understanding that members of the SNARE superfamily participate in diverse intracellular docking/fusion events, the physiological role of the majority of SNAREs in the intact organism remains elusive. In this study, through targeted gene knockout in mice, we establish that VAMP8/endobrevin is a major player in regulated exocytosis of the exocrine pancreas. VAMP8 is enriched on the membrane of...

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Source

Identifiers

PMID: 15363411
DOI: 10.1016/j.devcel.2004.08.002

Genes

VAMP8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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