Article
The role of Munc18-1 in docking and exocytosis of peptide hormone vesicles in the anterior pituitary.
Biology of the cell - 1 Jun 2005
Korteweg Niki, Maia Ascanio S, Thompson Brenda, Roubos Eric W, Burbach J Peter H, Verhage Matthijs
Abstract excerpt
BACKGROUND INFORMATION: Many neurons secrete classical transmitters from synaptic vesicles as well as peptide transmitters from LDCVs (large dense-core vesicles). Little is known about the mechanistic differences between these two secretory pathways. The soluble protein Munc18-1 is essential for synaptic vesicle secretion [Verhage, Maia, Plomp, Brussaard, Heeroma, Vermeer, Toonen, Hammer, van den Berg, Missler,...
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