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[The identification of Saccharomyces cerevisiae genes leading to synthetic lethality of prion [PSI+] with Sup45 mutations].

Molekuliarnaia biologiia - 1 Jan 2000

Matveenko A G, Zemlianko O M, Zhuravleva G A

Abstract excerpt

Previously, we proposed a test system allowing to perform search for genes that influence the properties of the Sup35 and Sup45 protein. This test is based on the phenomenon of lethality of diploids that combine mutations in SUP45 gene with [PSI+] prion. Lethality of this combination depends on the type of sup45 mutation, and the properties of the prion. [PSI+] variant, which is a strong suppressor ([PSI+]s),...

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PMID: 24466750
DOI: 10.7868/s0026898413040113

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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[The identification of Saccharomyces cerevisiae genes leading to synthetic lethality of prion [PSI+] with Sup45 mutations].PMID 24466750Read ↗

Nonsense Mutations in the Yeast SUP35 Gene Affect the [PSI+] Prion Propagation.Semantic proximity Read ↗

The PNM2 mutation in the prion protein domain of SUP35 has distinct effects on different variants of the [PSI+] prion in yeast.Semantic proximity Read ↗

Detection system- and strain-dependent diversity of de novo [PSI+] prion generation and phenotypes in Saccharomyces cerevisiae.Semantic proximity Read ↗

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[Fusion of glutathione S-transferase with the N-terminus of yeast Sup35p protein inhibits its prion-like properties].Semantic proximity Read ↗

[The characteristics of the prion-like element of yeast - mutant factor [PSI]].Semantic proximity Read ↗

Evidence for the prion hypothesis: induction of the yeast [PSI+] factor by in vitro- converted Sup35 protein.Semantic proximity Read ↗

The genetic control of the formation and propagation of the [PSI+] prion of yeast.Semantic proximity Read ↗

[New aspects of research upon the yeast Saccharomyces cerevisiae [PSI+] prion].Semantic proximity Read ↗

SFP1-mediated prion-dependent lethality is caused by increased Sup35 aggregation and alleviated by Sis1.Semantic proximity Read ↗

Guanidine reduces stop codon read-through caused by missense mutations in SUP35 or SUP45.Semantic proximity Read ↗

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