Article
[Fusion of glutathione S-transferase with the N-terminus of yeast Sup35p protein inhibits its prion-like properties].
Genetika - 1 May 1997
Dagkesamanskaia A R, Kushnirov V V, Paushkin S V, Ter-Avanesian M D
Abstract excerpt
The yeast Saccharomyces cerevisiae SUP35 gene that encodes the Sup35p protein homologous to the translation termination eRF3 factor of higher eukaryotes is essential to replication of the nonchromosomally inherited [psi+] determinant. The nonsense suppressor phenotype of this determinant was assu...
Topics
- Alleles
- DNA Replication
- Fungal Proteins
- Genes, Fungal
- Genes, Recessive
- Glutathione Transferase
- Heterozygote
- Peptide Termination Factors
- Prions
- Recombinant Fusion Proteins
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Sequence Deletion
- Terminator Regions, Genetic
