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Article

The PNM2 mutation in the prion protein domain of SUP35 has distinct effects on different variants of the [PSI+] prion in yeast.

Current genetics - 1 Mar 1999

Derkatch I L, Bradley M E, Zhou P, Liebman S W

Abstract excerpt

We have previously described different variants of the yeast prion [PSI+] that can be obtained and maintained in the same genetic background. These [PSI+] variants, which differ in the efficiency of nonsense suppression, mitotic stability and the efficiency of curing by GuHCl, may correspond to different [PSI+] prion conformations of Sup35p or to different types of prion aggregates. Here we investigate the...

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PMID: 10079323
DOI: 10.1007/s002940050433

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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The PNM2 mutation in the prion protein domain of SUP35 has distinct effects on different variants of the [PSI+] prion in yeast.PMID 10079323Read ↗

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Genetic and environmental factors affecting the de novo appearance of the [PSI+] prion in Saccharomyces cerevisiae.Semantic proximity Read ↗

Supporting the structural basis of prion strains: induction and identification of [PSI] variants.Semantic proximity Read ↗

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