Article
Polymorphisms in the p53 pathway genes and micronucleus occurrence in Chinese vinyl chloride-exposed workers.
International journal of occupational medicine and environmental health - 1 Dec 2013
Li Yong, Feng Nan-Nan, Zhang Guang-Hui, Wang Qi, Hao Yan-Hui, Ya-Nanzhang, Long Changxu, Li Yongliang, Brandt-Rauf Paul W, Xia Zhao-Lin
Abstract excerpt
OBJECTIVES: To investigate the association between polymorphisms in the p53 pathway genes and chromosomal damage in vinyl chloride (VC)-exposed workers. MATERIALS AND METHODS: Cytokinesis block micronucleus test was performed in 310 VC-exposed workers and 149 non-exposed workers to determine chromosomal damage. The polymerase chain reaction and restriction fragment length polymorphism technique were used to...
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