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Polymorphisms and haplotypes of DNA repair and xenobiotic metabolism genes and risk of DNA damage in Chinese vinyl chloride monomer (VCM)-exposed workers.

Toxicology letters - 5 May 2008

Zhu Shou-Min, Xia Zhao-Lin, Wang Ai-Hong, Ren Xue-Feng, Jiao Jie, Zhao Nai-Qing, Qian Ji, Jin Li, Christiani David C

Abstract excerpt

In this case-control study, we investigated the association between DNA damage and genetic susceptibility among vinyl chloride monomer (VCM)-exposed workers. The cumulative exposure dose of VCM was calculated based on the workers' duration of exposure and the geometric mean concentration of VCM in the workplace. DNA damage to peripheral blood lymphocytes was measured by single cell gel electrophoresis (SCGE)...

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Identifiers

PMID: 18420361
DOI: 10.1016/j.toxlet.2008.02.009

Genes

XRCC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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