Article
[Susceptibility of chromosomal damage among workers exposed to vinyl chloride monomer].
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases - 1 Aug 2011
Ji Fang, Zheng Ying-Jia, Wang Qi, Wang Wei, Qiu Yu-Lan, Wu Fen, Chai Shang-Jian, Li Jun, Xia Zhao-Lin
Abstract excerpt
OBJECTIVE: To explore the association between chromosomal damage induced by vinyl chloride monomer (VCM) and polymorphisms of xenobiotic metabolism genes and DNA repair genes. METHODS: Cytokinesis-block micronucleus (CBMN) test was performed to detect chromosomal damage in peripheral lymphocytes of 402 VCM-exposed workers. Multiplex PCR was used to simultaneously amplify GSTM1 and GSTT1 genes, other genetic...
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