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Article

Prevalence and persistence of chromosomal damage and susceptible genotypes of metabolic and DNA repair genes in Chinese vinyl chloride-exposed workers.

Carcinogenesis - 1 Apr 2010

Ji Fang, Wang Wei, Xia Zhao-Lin, Zheng Ying-Jia, Qiu Yu-Lan, Wu Fen, Miao Wen-Bin, Jin Ru-Feng, Qian Ji, Jin Li, Zhu Yi-Liang, Christiani David C

Abstract excerpt

Vinyl chloride (VC) was classified as a group 1 carcinogen by IARC in 1987. Although the relationship between VC exposure and liver cancer has been established, the mechanism of VC-related carcinogenesis remains largely unknown. Previous epidemiological studies have shown that VC exposure is associated with increased genotoxicity in humans. To explore chromosomal damage and its progression, and their association...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20100738
DOI: 10.1093/carcin/bgq015
PMCID: PMC3499047

Genes

ALDH2
GSTP1
XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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