Article
Mutations in apoptotic genes and micronucleus occurrence in vinyl chloride-exposed workers in China.
Environmental and molecular mutagenesis - 1 Jan 2017
Feng Nannan, Zheng Guoqiao, Hao Yanhui, Li Yong, Xu Yandan, Xu Xiaowen, Zhang Guanghui, Wang Jinwei, Li Yongliang, Brandt-Rauf Paul, Xia Zhao-Lin
Abstract excerpt
BACKGROUND: Vinyl chloride is an occupational carcinogen which caused micronuclei in human directly. It has recently been demonstrated that micronuclei formation could generate a spectrum of genomic rearrangements and play a key role in the early tumorigenesis process. We aimed to investigate the association between polymorphisms in the apoptosis process related genes and micronuclei rate in vinyl...
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