Article
DNA repair gene polymorphisms and micronucleus frequencies in Chinese workers exposed to vinyl chloride monomer.
International journal of hygiene and environmental health - 1 Jun 2011
Qiu Yu-lan, Wang Wei, Wang Tong, Sun Pin, Wu Fen, Zhu Shou-min, Qian Ji, Jin Li, Au William, Xia Zhao-lin
Abstract excerpt
Vinyl chloride monomer (VCM) is genotoxic and cancerogen agent. Individual variations in response to the exposure have been noticed and the variations may be due to genetic differences in the removal of VCM-DNA adducts, such as polymorphism in genes NER pathway and BER pathway. This study explores the relationship between genetic polymorphism of seven genes within the NER pathway (XPA, XPD, XPC, XPG, XPF, and...
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