Article
[Genetic susceptibility of DNA damage induced by vinyl chloride monomer exposure].
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases - 1 Jan 2010
Ji Fang, Zhu Shou-Min, Wang Ai-Hong, Qu Ya-Bin, Gu Shou-Yong, Zhu Ren, Cai Shang-Jian, Li Jun, Xia Zhao-Lin
Abstract excerpt
OBJECTIVE: To explore the association between DNA damage induced by vinyl chloride monomer (VCM) and polymorphisms of DNA repair genes and xenobiotic metabolism genes of VCM. METHODS: Comet assay was employed to detect DNA damage. Based on the status of DNA damage, the VCM exposure workers were divided into two groups: DNA damage group (75) and control group (75). Case-control design was used to investigate the...
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