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Article

Using single cell sequencing data to model the evolutionary history of a tumor.

BMC bioinformatics - 24 Jan 2014

Kim Kyung In, Simon Richard

Abstract excerpt

BACKGROUND: The introduction of next-generation sequencing (NGS) technology has made it possible to detect genomic alterations within tumor cells on a large scale. However, most applications of NGS show the genetic content of mixtures of cells. Recently developed single cell sequencing technology can identify variation within a single cell. Characterization of multiple samples from a tumor using single cell...

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Identifiers

PMID: 24460695
DOI: 10.1186/1471-2105-15-27
PMCID: PMC3903814

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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