Article
Genetic and phenotypic diversity in breast tumor metastases.
Cancer research - 1 Mar 2014
Almendro Vanessa, Kim Hee Jung, Cheng Yu-Kang, Gönen Mithat, Itzkovitz Shalev, Argani Pedram, van Oudenaarden Alexander, Sukumar Saraswati, Michor Franziska, Polyak Kornelia
Abstract excerpt
Metastatic disease is the main cause of cancer-related mortality due to almost universal therapeutic resistance. Despite its high clinical relevance, our knowledge of how cancer cell populations change during metastatic progression is limited. Here, we investigated intratumor genetic and phenotyp...
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