Article
Heterogeneity and cancer.
Oncology (Williston Park, N.Y.) - 1 Sept 2014
Allison Kimberly H, Sledge George W
Abstract excerpt
Cancer heterogeneity, long recognized as an important clinical determinant of patient outcomes, was poorly understood at a molecular level. Genomic studies have significantly improved our understanding of heterogeneity, and have pointed to ways in which heterogeneity might be understood and defeated for therapeutic effect. Recent studies have evaluated intratumoral heterogeneity within the primary tumor, as well...
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