Article
Mitochondrial control region alterations and breast cancer risk: a study in South Indian population.
PloS one - 1 Jan 2014
Tipirisetti Nageswara Rao, Govatati Suresh, Pullari Priyanka, Malempati Sravanthi, Thupurani Murali Krishna, Perugu Shyam, Guruvaiah Praveen, Rao K Lakshmi, Digumarti Raghunadha Rao, Nallanchakravarthula Varadacharyulu, Bhanoori Manjula, Satti Vishnupriya
Abstract excerpt
BACKGROUND: Mitochondrial displacement loop (D-loop) is the hot spot for mitochondrial DNA (mtDNA) alterations which influence the generation of cellular reactive oxygen species (ROS). Association of D-loop alterations with breast cancer has been reported in few ethnic groups; however none of the reports were documented from Indian subcontinent. METHODOLOGY: We screened the entire mitochondrial D-loop region...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.