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Article

Influence of genetic polymorphisms involved in the hypothalamic-pituitary-adrenal axis and their interactions with environmental factors on antidepressant response.

CNS neuroscience & therapeutics - 1 Mar 2014

Geng Lei-Yu, Ye Dong-Qing, Shi Yan-Yan, Xu Zhi, Pu Meng-Jia, Li Zan-Yuan, Li Xiao-Li, Li Yang, Zhang Zhi-Jun

Abstract excerpt

AIMS: To investigate the role of genetic polymorphisms in candidate genes associated with the HPA axis and their interactions with environmental stressors in antidepressant response. METHODS: The remission of depressive symptoms after 8 weeks of antidepressant treatment was tested against 21 single nucleotide polymorphisms (SNPs) in five candidate genes associated with the HPA axis in a Chinese Han sample...

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Source

Open in PubMed Open full text

Identifiers

PMID: 24422887
DOI: 10.1111/cns.12201
PMCID: PMC6493124

Genes

CRHR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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