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Article

Association analysis for corticotropin releasing hormone polymorphisms with the risk of major depressive disorder and the response to antidepressants.

Behavioural brain research - 1 Oct 2015

Chang Hun Soo, Won Eunsoo, Lee Hwa-Young, Ham Byung-Joo, Lee Min-Soo

Abstract excerpt

Hyperactivity of the hypothalamic-pituitary-adrenal (HPA) axis is one of the most consistent neuroendocrine abnormalities observed in patients with major depressive disorder (MDD). The peptide corticotropin-releasing hormone (CRH) is a key mediator for HPA axis function during stress. This study evaluated the associations of CRH polymorphisms with susceptibility to MDD and response to antidepressant treatment,...

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Share to Antidepressive Agents
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Citalopram

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Source

Identifiers

PMID: 26055202
DOI: 10.1016/j.bbr.2015.06.005

Genes

CRH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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