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Article

Base-resolution maps of 5-methylcytosine and 5-hydroxymethylcytosine in Dahl S rats: effect of salt and genomic sequence.

Hypertension (Dallas, Tex. : 1979) - 1 Apr 2014

Liu Yong, Liu Pengyuan, Yang Chun, Cowley Allen W, Liang Mingyu

Abstract excerpt

Analysis of 5-hydroxymethylcytosine (5hmC) at single-base resolution has been largely limited to studies of stem cells or developmental stages. Given the potential importance of epigenetic events in hypertension, we have analyzed 5hmC and 5-methylcytosine (5mC) at single-base resolution in the renal outer medulla of the Dahl salt-sensitive rat and examined the effect of disease-relevant genetic or environmental...

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Identifiers

PMID: 24420542
DOI: 10.1161/HYPERTENSIONAHA.113.02637
PMCID: PMC4315612

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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