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Article

Short‐term calorie restriction ameliorates genomewide, age‐related alterations in<scp>DNA</scp>methylation

25 Aug 2016

Abstract excerpt

DNA methylation plays major roles in many biological processes, including aging, carcinogenesis, and development. Analyses of DNA methylation using next-generation sequencing offer a new way to profile and compare methylomes across the genome in the context of aging. We explored genomewide DNA methylation and the effects of short-term calorie restriction (CR) on the methylome of aged rat kidney. Whole-genome...

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PMID: 27561685
DOI: 10.1111/acel.12513

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