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Article

A four-amino acid linker between repeats in the α-synuclein sequence is important for fibril formation.

Biochemistry - 21 Jan 2014

Shvadchak Volodymyr V, Subramaniam Vinod

Abstract excerpt

α-Synuclein is a 140-amino acid protein that can switch conformation among intrinsically disordered in solution, helical on a membrane, and β-sheet in amyloid fibrils. Using the fluorescence of single-tryptophan mutants, we determined the immersion of different regions of the protein into lipid m...

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PMID: 24397337
DOI: 10.1021/bi401427t

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24397337-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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