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Article

Interaction of alpha-synuclein with lipids.

Methods in cell biology - 1 Jan 2022

Kachappilly Neha, Srivastava Jyotirmay, Swain Bani Prasad, Thakur Poonam

Abstract excerpt

Alpha-synuclein (α-syn) is a natively unfolded protein that is abundantly expressed in the central nervous system. Although it has been shown to be involved in neurotransmission and cognition, its exact functions remain elusive. The misfolding of this protein into β-sheet-rich amyloid structures and subsequent aggregation has been associated with several neurodegenerative diseases, including Parkinson's disease....

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PMID: 35623711
DOI: 10.1016/bs.mcb.2021.12.002

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