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Article

A mouse model with tamoxifen‐inducible thyrocyte‐specific cre recombinase activity

7 Jan 2014

Abstract excerpt

We have created a mouse model expressing tamoxifen-inducible Cre recombinase (CreER(T2) ) under the control of the thyroglobulin (Tg) gene promoter to be able to study the role of defined genetic modifications in the regulation of thyroid function. We chose the thyroglobulin promoter, as it is expressed specifically in the thyroid. In order to obtain reliable expression under the control of the Tg promoter, we...

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PMID: 24395757
DOI: 10.1002/dvg.22740

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