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Article

Early cellular abnormalities induced by RET/PTC1 oncogene in thyroid-targeted transgenic mice.

Oncogene - 17 Jun 1999

Cho J Y, Sagartz J E, Capen C C, Mazzaferri E L, Jhiang S M

Abstract excerpt

The RET/PTC1 oncogene, a rearranged form of the RET proto-oncogene, has been reported to be associated with human papillary thyroid carcinomas. We have shown that targeted expression of RET/PTC1 in the thyroid gland leads to the development of thyroid carcinomas in transgenic mice with histologic...

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Source

Identifiers

PMID: 10380889
DOI: 10.1038/sj.onc.1202709

Genes

RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-10380889-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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