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Article

Inducible gene inactivation in neurons of the adult mouse forebrain.

BMC neuroscience - 2 Aug 2007

Erdmann Gitta, Schütz Günther, Berger Stefan

Abstract excerpt

BACKGROUND: The analysis of the role of genes in important brain functions like learning, memory and synaptic plasticity requires gene inactivation at the adult stage to exclude developmental effects, adaptive changes or even lethality. In order to achieve temporally controlled somatic mutagenesis, the Cre/loxP-recombination system has been complemented with the tamoxifen-inducible fusion protein consisting of...

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PMID: 17683525
DOI: 10.1186/1471-2202-8-63
PMCID: PMC1955451

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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