Article
[Biological characteristics of cleft palate relevant gene thyroid transcription factor-2 transgenic mice].
Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology - 1 Aug 2014
Huang Lei, Shi Bing, Qian Zheng, Meng Tian, Wang Yan
Abstract excerpt
OBJECTIVE: The aim of this study is to establish a transgenic mouse model for cleft palate relevant gene thyroid transcription factor-2 (TTF-2), which can be used to study palatal shelf development when the expression pattern and regular activation of TTF-2 is altered. METHODS: The C57BL/6J mouse TTF-2 gene was cloned through polymerase chain reaction (PCR) from the mouse genomic DNA. The TTF-2 gene was inserted...
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