Article
The influence of polygenic risk scores on heritability of anti-CCP level in RA.
Genes and immunity - 1 Mar 2014
Cui J, Taylor K E, Lee Y C, Källberg H, Weinblatt M E, Coblyn J S, Klareskog L, Criswell L A, Gregersen P K, Shadick N A, Plenge R M, Karlson E W
Abstract excerpt
The objective of this study was to study genetic factors that influence quantitative anticyclic citrullinated peptide (anti-CCP) antibody levels in RA patients. We carried out a genome-wide association study (GWAS) meta-analysis using 1975 anti-CCP+ RA patients from three large cohorts, the Brigham Rheumatoid Arthritis Sequential Study (BRASS), North American Rheumatoid Arthritis Consortium (NARAC) and the...
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