Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A weighted genetic risk score using all known susceptibility variants to estimate rheumatoid arthritis risk.

Annals of the rheumatic diseases - 1 Jan 2015

Yarwood Annie, Han Buhm, Raychaudhuri Soumya, Bowes John, Lunt Mark, Pappas Dimitrios A, Kremer Joel, Greenberg Jeffrey D, Plenge Robert, Worthington Jane, Barton Anne, Eyre Steve

Abstract excerpt

BACKGROUND: There is currently great interest in the incorporation of genetic susceptibility loci into screening models to identify individuals at high risk of disease. Here, we present the first risk prediction model including all 46 known genetic loci associated with rheumatoid arthritis (RA). METHODS: A weighted genetic risk score (wGRS) was created using 45 RA non-human leucocyte antigen (HLA) susceptibility...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arthritis, Rheumatoid
Share to HLA-B Antigens

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to HLA-DP beta-Chains

Share to HLA-DRB1 Chains

Share to Logistic Models

Share to Peptides, Cyclic

Share to Risk Assessment

Share to Sex Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 24092415
DOI: 10.1136/annrheumdis-2013-204133
PMCID: PMC4283663

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A weighted genetic risk score using all known susceptibility variants to estimate rheumatoid arthritis risk.PMID 24092415Read ↗

Cumulative association of 22 genetic variants with seropositive rheumatoid arthritis risk.Semantic proximity Read ↗

Genetics of rheumatoid arthritis: what have we learned?Semantic proximity Read ↗

Genetic risk scores and number of autoantibodies in patients with rheumatoid arthritis.Semantic proximity Read ↗

Role of Selected Genetic Polymorphisms in the Development of Rheumatoid Arthritis in a British White Population.Semantic proximity Read ↗

A genome-wide association study of rheumatoid arthritis without antibodies against citrullinated peptides.Semantic proximity Read ↗

The genetic puzzle of rheumatoid arthritis: Causes, progression, and treatmentSemantic proximity Read ↗

Association of environmental and genetic factors and gene-environment interactions with risk of developing rheumatoid arthritis.Semantic proximity Read ↗

Genetic Risk Scores for the Clinical Rheumatologist.Semantic proximity Read ↗

Genetic variants in the prediction of rheumatoid arthritis.Semantic proximity Read ↗

Genetic markers of rheumatoid arthritis susceptibility in anti-citrullinated peptide antibody negative patients.Semantic proximity Read ↗

Update on the genetic risk factors for rheumatoid arthritis.Semantic proximity Read ↗

The genetic architecture of rheumatoid arthritis: from susceptibility to clinical subphenotype associations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.