Article
The genetic architecture of rheumatoid arthritis: from susceptibility to clinical subphenotype associations.
Current topics in medicinal chemistry - 1 Jan 2013
Julià Antonio, Marsal Sara
Abstract excerpt
Rheumatoid Arthritis (RA) is the most common chronic inflammatory disease of the joints and is characterized by a complex genetic architecture. In recent years, a substantial advance has been performed in the identification of the genes that increase the risk to develop RA. Genome-Wide Association Studies (GWAS) have allowed the characterization of more than 40 new susceptibility genes and the confirmation of a...
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