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Article

Contribution of a haplotype in the HLA region to anti-cyclic citrullinated peptide antibody positivity in rheumatoid arthritis, independently of HLA-DRB1.

Arthritis and rheumatism - 1 Dec 2009

Okada Yukinori, Yamada Ryo, Suzuki Akari, Kochi Yuta, Shimane Kenichi, Myouzen Keiko, Kubo Michiaki, Nakamura Yusuke, Yamamoto Kazuhiko

Abstract excerpt

OBJECTIVE: To examine the risk of anti-cyclic citrullinated peptide (anti-CCP) antibody positivity in rheumatoid arthritis (RA) patients carrying certain haplotypes in the HLA region. METHODS: A total of 1,389 Japanese patients with RA were genotyped for 30 single-nucleotide polymorphisms (SNPs) in the HLA region using commercial oligonucleotide arrays (from Perlegen or Affymetrix) as well as for HLA-DRB1 alleles...

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Share to Arthritis, Rheumatoid
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

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Share to HLA-DR Antigens

Share to HLA-DRB1 Chains

Share to Peptides, Cyclic

Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 19950296
DOI: 10.1002/art.24939

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