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Article

Genetic association between mitochondrial DNA copy number and glioma risk: insights from causality.

BMC cancer - 21 Nov 2024

He Qiang, Wang Wenjing, Xu Dingkang, Xiong Yang, Tao Chuanyuan, Ma Lu, Ma Junpeng, Zheng Songping, You Chao, Zan Xin

Abstract excerpt

BACKGROUND: The genetic causal association between the mitochondrial DNA copy number (mtDNA-CN) and the development of glioma and glioblastoma (GBM) remains unclear. METHODS: The summary-level datasets for mtDNA-CN were obtained from participants in the UK Biobank and the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium. Additionally, summary statistics datasets related to glioma were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39574033
DOI: 10.1186/s12885-024-13212-7
PMCID: PMC11583505

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