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Article

Correlation of N-acetyltransferase 2 genotype with isoniazid acetylation in Polish tuberculosis patients.

BioMed research international - 1 Jan 2013

Zabost Anna, Brzezińska Sylwia, Kozińska Monika, Błachnio Maria, Jagodziński Jacek, Zwolska Zofia, Augustynowicz-Kopeć Ewa

Abstract excerpt

UNLABELLED: Isoniazid (INH), a key agent in the treatment of tuberculosis (TB), is metabolized primarily by the genetically polymorphic N-acetyltransferase 2 (NAT2) enzyme. Patients treated with INH can be classified as fast, intermediate, and slow acetylators. The objective of this study was to explore the relationship between NAT2 genotypes and the serum concentrations of INH. Blood samples from 130 patients...

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Share to Acetylation
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Arylamine N-Acetyltransferase

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Source

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Identifiers

PMID: 24383060
DOI: 10.1155/2013/853602
PMCID: PMC3871508

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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