Article
N-acetyltransferase gene polymorphisms & plasma isoniazid concentrations in patients with tuberculosis.
The Indian journal of medical research - 1 Jan 2017
Hemanth Kumar A K, Ramesh K, Kannan T, Sudha V, Haribabu Hemalatha, Lavanya J, Swaminathan Soumya, Ramachandran Geetha
Abstract excerpt
BACKGROUND & OBJECTIVES: Variations in the N-acetyltransferase (NAT2) gene among different populations could affect the metabolism and disposition of isoniazid (INH). This study was performed to genotype NAT2 gene polymorphisms in tuberculosis (TB) patients from Chennai, India, and compare plasma INH concentrations among the different genotypes. METHODS: Adult patients with TB treated in the Revised National TB...
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