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Article

[Detection of mutation in NAT II gene as a method of determination of izoniazyd (INH) acetylation type in human population].

Pneumonologia i alergologia polska - 1 Jan 2007

Augustynowicz-Kopeć Ewa, Zabost Anna, Kozińska Monika, Brzezińska Sylwia, Zwolska Zofia

Abstract excerpt

INTRODUCTION: Isoniazid (INH) is a drug widely used in the treatment of tuberculosis. INH is metabolized to acetylisoniazid by N-acetyltransferase (NAT) in the liver. The rate of INH acetylation is genetically determined. NAT isozymes are encoded at 2 loci; one encodes NAT1, formerly known as the monomorphic form of the enzyme, while the other encodes the polymorphic NAT2, which is responsible for individual...

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Share to Acetylation
Share to Arylamine N-Acetyltransferase

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genotype

Share to Isoniazid

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Share to Polymorphism, Genetic

Share to Tuberculosis, Pulmonary

Source

Identifiers

PMID: 17973219

Genes

NAT2
NAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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[Detection of mutation in NAT II gene as a method of determination of izoniazyd (INH) acetylation type in human population].PMID 17973219Read ↗

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