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Article

Genetic and neuroanatomic associations in sporadic frontotemporal lobar degeneration.

Neurobiology of aging - 1 Jun 2014

McMillan Corey T, Toledo Jon B, Avants Brian B, Cook Philip A, Wood Elisabeth M, Suh Eunran, Irwin David J, Powers John, Olm Christopher, Elman Lauren, McCluskey Leo, Schellenberg Gerard D, Lee Virginia M-Y, Trojanowski John Q, Van Deerlin Vivianna M, Grossman Murray

Abstract excerpt

Genome-wide association studies have identified single nucleotide polymorphisms (SNPs) that are sensitive for tau or TDP-43 pathology in frontotemporal lobar degeneration (FTLD). Neuroimaging analyses have revealed distinct distributions of disease in FTLD patients with genetic mutations. However...

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Identifiers

PMID: 24373676
DOI: 10.1016/j.neurobiolaging.2013.11.029
PMCID: PMC3961542

Genes

MAPT
MOBP
SORT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24373676-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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