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Article

Common genetic variation is associated with longitudinal decline and network features in behavioral variant frontotemporal degeneration.

Neurobiology of aging - 1 Dec 2021

Massimo Lauren, Rennert Lior, Xie Sharon X, Olm Christopher, Bove Jessica, Van Deerlin Vivianna, Irwin David J, Grossman Murray, McMillan Corey T

Abstract excerpt

The T allele in rs1768208 located in or near the myelin oligodendrocyte basic protein gene (MOBP) is a risk factor for frontotemporal degeneration pathology. We evaluated the hypothesis that the presence of a T allele in rs1768208 will be associated with rate of cognitive decline in behavioral variant frontotemporal degeneration (bvFTD) related to compromised frontal networks. We studied 81 individuals clinically...

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Identifiers

PMID: 34474300
DOI: 10.1016/j.neurobiolaging.2021.07.018
PMCID: PMC8616801

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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