Article
Profiles of white matter tract pathology in frontotemporal dementia.
Human brain mapping - 1 Aug 2014
Mahoney Colin J, Ridgway Gerard R, Malone Ian B, Downey Laura E, Beck Jonathan, Kinnunen Kirsi M, Schmitz Nicole, Golden Hannah L, Rohrer Jonathan D, Schott Jonathan M, Rossor Martin N, Ourselin Sebastien, Mead Simon, Fox Nick C, Warren Jason D
Abstract excerpt
Despite considerable interest in improving clinical and neurobiological characterisation of frontotemporal dementia and in defining the role of brain network disintegration in its pathogenesis, information about white matter pathway alterations in frontotemporal dementia remains limited. Here we investigated white matter tract damage using an unbiased, template-based diffusion tensor imaging (DTI) protocol in a...
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