Article
Association between genetic variations in the insulin/insulin-like growth factor (Igf-1) signaling pathway and longevity: a systematic review and meta-analysis.
Current vascular pharmacology - 1 Jan 2014
Di Bona Danilo, Accardi Giulia, Virruso Claudia, Candore Giuseppina, Caruso Calogero
Abstract excerpt
Some studies have shown that polymorphisms in the insulin growth factor-1 (IGF-1) signaling pathway genes could influence human longevity. However, the results of different studies are often inconsistent. Our aim was to investigate by systematic review and meta-analysis the association of the common polymorphisms defining the genetic variability of the IGF-1 signaling pathway associated with human longevity....
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