Article
The impacts of single nucleotide polymorphisms in genes of cell cycle and NF-kB pathways on the efficacy and acute toxicities of radiotherapy in patients with nasopharyngeal carcinoma.
Oncotarget - 11 Apr 2017
Guo Chengxian, Huang Yuling, Yu Jingjing, Liu Lijuan, Gong Xiaochang, Huang Min, Jiang Chunling, Liao Yulu, Huang Lihua, Yang Guoping, Li Jingao
Abstract excerpt
Radiotherapy is one of the primary choices for the treatment of nasopharyngeal carcinoma (NPC) and may result in severe radiotoxicities on normal tissues. Single nucleotide polymorphisms (SNPs) in genes of cell cycle and NF-κB pathways have been linked with the prognoses of various cancers. The aim of this study was to explore whether SNPs of genes involved in cell cycle and NF-κB pathways are associated with...
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