Article
Surveillance of the tumor mutanome by T cells during progression from primary to recurrent ovarian cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Mar 2014
Wick Darin A, Webb John R, Nielsen Julie S, Martin Spencer D, Kroeger David R, Milne Katy, Castellarin Mauro, Twumasi-Boateng Kwame, Watson Peter H, Holt Rob A, Nelson Brad H
Abstract excerpt
PURPOSE: Cancers accumulate mutations over time, each of which brings the potential for recognition by the immune system. We evaluated T-cell recognition of the tumor mutanome in patients with ovarian cancer undergoing standard treatment. EXPERIMENTAL DESIGN: Tumor-associated T cells from 3 patie...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
