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Article

Neoantigens in Ovarian Cancer: Embarrassment of Riches or Needles in a Haystack?

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Nov 2018

McNeish Iain A

Abstract excerpt

Comprehensive genomic and transcriptomic analysis demonstrate that tumor-infiltrating T lymphocytes that react to mutated neoepitopes could be identified in recurrent ovarian cancer. Two of these T-cell populations reacted against TP53 hotspot missense mutations that are present in a wide variety of malignancies. Clin Cancer Res; 24(22); 5493-5. ©2018 AACR See related article by Deniger et al., p. 5562.

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Share to Lymphocytes, Tumor-Infiltrating
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Share to Neoplasm Recurrence, Local

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29980529
DOI: 10.1158/1078-0432.CCR-18-1731
PMCID: PMC6215482

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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Neoantigens in Ovarian Cancer: Embarrassment of Riches or Needles in a Haystack?PMID 29980529Read ↗

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Induction of Neoantigen-Specific Cytotoxic T Cells and Construction of T-cell Receptor-Engineered T Cells for Ovarian Cancer.Semantic proximity Read ↗

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