Article

The mutational load and a T-cell inflamed tumor phenotype identify ovarian cancer patients rendering tumor-reactive T cells from PD-1+ tumor-infiltrating lymphocytes

2020-05-01

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Adoptive immunotherapy with tumor-infiltrating lymphocytes (TIL) may benefit from the use of selective markers, such as programmed cell death protein 1 (PD-1), for tumor-specific T-cell enrichment, as well as predictive biomarkers that help identify those patients capable of rendering tumor-reactive TIL products. We have investigated this in ovarian cancer (OC)...

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Literature Corpus work: 9c3a4692-acf8-5e07-bfcb-c059c4496306
DOI: 10.21203/rs.3.rs-25670/v1

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