Article

Myeloid cell networks determine reinstatement of original immune environments in recurrent ovarian cancer

2024-05-05

Abstract excerpt

<h4>Summary</h4> Immunotherapy has produced disappointing results in recurrent ovarian cancer (OC). However, the prognostic value of tumour-infiltrating lymphocytes (TILs) is largely based on the analysis of treatment-naive tumours. To understand the immunobiology of recurrent cancers, and their evolution, we profiled 170 patient-matched primary-recurrent OC samples from 69 patients of two independent cohorts. By...

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Literature Corpus work: 2d5d5057-29de-5ac0-ad76-13b026e26c2a
DOI: 10.1101/2024.05.02.590528

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